No data on the use of angiotensin II receptor antagonists are available. These agents are also small enough to pass into breast milk, and some unpublished studies have found them in the milk of lactating rats. However, most angiotensin II receptor antagonists are highly bound to maternal plasma proteins, which can substantially limit their transfer into breast milk.
The effects of potential exposure on a nursing infant are unknown. For all angiotensin II receptor antagonists, use in mothers breastfeeding is not recommended. Alternative antihypertensive treatments with more established safety profiles during breastfeeding are preferable, especially while nursing a newborn or preterm baby. See also clarification published July for more information.
Cooper WO, et al. N Engl J Med ; — J Clin Pharmacol ; — Redman CW, et al. Eur J Clin Pharmacol ; Begg EJ, et al.
Br J Clin Pharmacol ; — To help us improve GOV. It will take only 2 minutes to fill in. ACE inhibitors work better for younger people than for older people. They also work better for white people than for black people. Your doctor may recommend a different medication.
Doctors commonly prescribe ACE inhibitors because they don't often cause side effects. In rare cases, particularly for black people, women and smokers, ACE inhibitors can cause some areas of the tissues to swell angioedema. If swelling occurs in the throat, it can be life-threatening. ACE inhibitors can be harmful to you and your baby during pregnancy. If you're pregnant or plan to become pregnant, talk to your doctor about other options to treat high blood pressure.
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Angiotensin-converting enzyme ACE inhibitors ACE inhibitors are commonly prescribed to treat high blood pressure, heart problems and other conditions. By Mayo Clinic Staff. References Mann JFE. Choice of drug therapy in primary essential hypertension. Accessed June 25, Types of blood pressure medications. American Heart Association. Sidawy AN, et al. Atherosclerotic risk factors: Hypertension.
Philadelphia, Pa. Accessed July 11, Beta-blockers slow the heartbeat and lower the stress on the heart. Diuretics make your kidneys release more water. This reduces how much volume your heart has to pump.
They may be used for:. Eur Heart J ;— Get free access to newly published articles Create a personal account or sign in to: Register for email alerts with links to free full-text articles Access PDFs of free articles Manage your interests Save searches and receive search alerts. American College of Rheumatology. Advertising revenue supports our not-for-profit mission.
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Types of ACE inhibitors. Benefits of ACE inhibitors. Side effects of ACE inhibitors. Taking your medication. Q: How do ACE inhibitors compare to other types of medications used to treat hypertension? A: ACE inhibitors cause your blood vessels to relax and reduce the pressure your heart has to push against. Alan Carter, PharmD Answers represent the opinions of our medical experts.